Embryo Screening Tool

Here’s the logic behind it:

1. Embryos inherit different parts of each of their parents’ genomes. This leads to genetic variation.

2. This variation gives rise to differences in genetic risks of disease, some of which we can capture with our polygenic scores.

→ Given information about the prospective parents (ancestry and disease status), we can simulate sets of embryos with realistic genetic variation and identify those at the highest, lowest, and average genetic risk. This tool helps prospective parents understand how well our predictors can stratify risk of disease among their embryos.